By The Hudsonian, Joshua Hudson
| Click Here for: | RB | WR | FLEX | TE | D/ST |
| Quarterback | Team | Opponent | |
| 1 | Ben Roethlisberger | PIT | at CLE |
| 2 | Drew Brees | NO | at CAR |
| 3 | Marcus Mariota | TEN | at IND |
| 4 | Tom Brady | NE | at SF |
| 5 | Andrew Luck | IND | TEN |
| 6 | Cam Newton | CAR | NO |
| 7 | Aaron Rodgers | GB | at WSH |
| 8 | Kirk Cousins | WSH | GB |
| 9 | Tyrod Taylor | BUF | at CIN |
| 10 | Derek Carr | OAK | HOU |
| 11 | Blake Bortles | JAX | at DET |
| 12 | Matthew Stafford | DET | at JAX |
| 13 | Colin Kaepernick | SF | NE |
| 14 | Russell Wilson | SEA | PHI |
| 15 | Dak Prescott | DAL | BAL |
| 16 | Carson Palmer | ARI | at MIN |
| 17 | Eli Manning | NYG | CHI |
| 18 | Jameis Winston | TB | at KC |
| 19 | Andy Dalton | CIN | BUF |
| 20 | Joe Flacco | BAL | at DAL |
| 21 | Alex Smith | KC | TB |
| 22 | Cody Kessler | CLE | PIT |
| 23 | Ryan Tannehill | MIA | at LA |
| 24 | Carson Wentz | PHI | at SEA |
| 25 | Jay Cutler | CHI | at NYG |
| 26 | Sam Bradford | MIN | ARI |
| 27 | Brock Osweiler | HOU | at OAK |
| 28 | Jared Goff | LA | MIA |
** Bye Weeks: Broncos, Chargers, Falcons & Jets **