By The Hudsonian, Joshua Hudson
| Click Here for: | QB | WR | FLEX | TE | D/ST |
| RB | Team | Opponent | |
| 1 | David Johnson | ARI | SF |
| 2 | Ezekiel Elliott | DAL | at PIT |
| 3 | Le’Veon Bell | PIT | DAL |
| 4 | Melvin Gordon | SD | MIA |
| 5 | Jay Ajayi | MIA | at SD |
| 6 | Lamar Miller | HOU | at JAX |
| 7 | DeMarco Murray | TEN | GB |
| 8 | Terrance West | BAL | CLE |
| 9 | Matt Forte | NYJ | LA |
| 10 | Spencer Ware | KC | at CAR |
| 11 | Devonta Freeman | ATL | at PHI |
| 12 | Devontae Booker | DEN | at NO |
| 13 | Darren Sproles | PHI | ATL |
| 14 | Jordan Howard | CHI | at TB |
| 15 | Todd Gurley | LA | at NYJ |
| 16 | Giovani Bernard | CIN | at NYG |
| 17 | Jonathan Stewart | CAR | KC |
| 18 | Peyton Barber | TB | CHI |
| 19 | Mark Ingram | NO | DEN |
| 20 | Ty Montgomery | GB | at TEN |
| 21 | James White | NE | SEA |
| 22 | LeGarrette Blount | NE | SEA |
| 23 | Duke Johnson Jr. | CLE | at BAL |
| 24 | Carlos Hyde | SF | at ARI |
| 25 | Christine Michael | SEA | at NE |
| 26 | Isaiah Crowell | CLE | at BAL |
| 27 | Rashad Jennings | NYG | CIN |
| 28 | Jeremy Hill | CIN | at NYG |
| 29 | Tevin Coleman | ATL | at PHI |
| 30 | Paul Perkins | NYG | CIN |
| 31 | C.J. Prosise | SEA | at NE |
| 32 | Tim Hightower | NO | DEN |
| 33 | T.J. Yeldon | JAX | HOU |
| 34 | Chris Ivory | JAX | HOU |
| 35 | Jerrick McKinnon | MIN | at WSH |
| 36 | Charcandrick West | KC | at CAR |
| 37 | Robert Kelley | WSH | MIN |
| 38 | Bilal Powell | NYJ | LA |
| 39 | Matt Asiata | MIN | at WSH |
| 40 | Chris Thompson | WSH | MIN |
| 41 | Ryan Mathews | PHI | ATL |
** Bye Weeks: Bills, Colts, Lions & Raiders **