By Chris Molina
| Rank | Running Backs | Team |
| 1 | Christian McCaffrey | CAR |
| 2 | Saquon Barkley | NYG |
| 3 | Alvin Kamara | NO |
| 4 | Todd Gurley | LAR |
| 5 | Ezekiel Elliot | DAL |
| 6 | David Johnson | ARI |
| 7 | James Conner | PIT |
| 8 | Le’Veon Bell | NYJ |
| 9 | Nick Chubb | CLE |
| 10 | Dalvin Cook | MIN |
| 11 | Joe Mixon | CIN |
| 12 | Devonta Freeman | ATL |
| 13 | Kerryon Johnson | DET |
| 14 | Damien Williams | KC |
| 15 | Aaron Jones | GB |
| 16 | Leonard Fournette | JAX |
| 17 | Josh Jacobs* | OAK |
| 18 | David Montgomery* | CHI |
| 19 | Melvin Gordon | LAC |
| 20 | Chris Carson | SEA |
| 21 | Sony Michel | NE |
| 22 | Derrick Henry | TEN |
| 23 | Marlon Mack | IND |
| 24 | Tevin Coleman | SF |
| 25 | Kenyan Drake | MIA |
| 26 | Phillip Lindsay | DEN |
| 27 | Miles Sanders* | PHI |
| 28 | Mark Ingram | BAL |
| 29 | James White | NE |
| 30 | Duke Johnson Jr. | HOU |
| 31 | Tarik Cohen | CHI |
| 32 | Austin Ekeler | LAC |
| 33 | Latavius Murray | NO |
| 34 | Rashaad Penny | SEA |
| 35 | Royce Freeman | DEN |
| 36 | Derrius Guice | WAS |
| 37 | Peyton Barber | TB |
| 38 | Kalen Ballage | MIA |
| 39 | Matt Breida | SF |
| 40 | LeSean McCoy | BUF |
| 41 | Darwin Thompson* | KC |
| 42 | Dion Lewis | TEN |
| 43 | Adrian Peterson | WAS |
| 44 | Tony Pollard* | DAL |
| 45 | Jordan Howard | PHI |
| 46 | Justin Jackson | LAC |
| 47 | Nyheim Hines | IND |
| 48 | Alexander Mattison* | MIN |
| 49 | Devin Singletary* | BUF |
| 50 | Ronald Jones | TB |
| 51 | Malcolm Brown | LAR |
| 52 | Darrell Henderson* | LAR |
| 53 | Damien Harris* | NE |
| 54 | Chris Thompson | WAS |
| 55 | Jaylen Samuels | PIT |
| 56 | Justice Hill* | BAL |
| 57 | Jerick McKinnon | SF |
| 58 | Frank Gore | BUF |
| 59 | Mike Davis | CHI |
| 60 | Ito Smith | ATL |