By The Hudsonian, Joshua Hudson
| Click Here for: | QB | WR | FLEX | TE | D/ST |
| RB | Team | Opponent | |
| 1 | Le’Veon Bell | PIT | at CIN |
| 2 | DeVonta Freeman | ATL | SF |
| 3 | David Johnson | ARI | NO |
| 4 | LeSean McCoy | BUF | CLE |
| 5 | Latavius Murray | OAK | at SD |
| 6 | Ezekiel Elliott | DAL | TB |
| 7 | Jay Ajayi | MIA | at NYJ |
| 8 | Jordan Howard | CHI | GB |
| 9 | Thomas Rawls | SEA | LA |
| 10 | Carlos Hyde | SF | at ATL |
| 11 | DeMarco Murray | TEN | at KC |
| 12 | Bilal Powell | NYJ | MIA |
| 13 | Isaiah Crowell | CLE | at BUF |
| 14 | Jonathan Stewart | CAR | at WSH |
| 15 | Lamar Miller | HOU | JAX |
| 16 | Theo Riddick | DET | at NYG |
| 17 | LeGarrette Blount | NE | at DEN |
| 18 | Tevin Coleman | ATL | SF |
| 19 | Frank Gore | IND | at MIN |
| 20 | Spencer Ware | KC | TEN |
| 21 | Kenneth Farrow | SD | OAK |
| 22 | Robert Kelley | WSH | CAR |
| 23 | Ty Montgomery | GB | at CHI |
| 24 | Doug Martin | TB | at DAL |
| 25 | Rashad Jennings | NYG | DET |
| 26 | Mark Ingram | NO | at ARI |
| 27 | Kenneth Dixon | BAL | PHI |
| 28 | Matt Asiata | MIN | IND |
| 29 | Jerick McKinnon | MIN | IND |
| 30 | Todd Gurley | LA | at SEA |
| 31 | Duke Johnson Jr. | CLE | at BUF |
| 32 | Rex Burkhead | CIN | PIT |
| 33 | Dion Lewis | NE | at DEN |
| 34 | T.J. Yeldon | JAX | at HOU |
| 35 | James White | NE | at DEN |
| 36 | Justin Forsett | DEN | NE |
| 37 | Ryan Mathews | PHI | at BAL |
| 38 | Terrance West | BAL | PHI |
| 39 | Tim Hightower | NO | at ARI |
| 40 | Charles Sims | TB | at DAL |
| 41 | Shaun Draughn | SF | at ATL |
| 42 | Jalen Richard | OAK | at SD |
| 43 | Chris Thompson | WSH | CAR |
| 44 | Dwayne Washington | DET | at NYG |
| 45 | Devontae Booker | DEN | NE |