By The Hudsonian, Joshua Hudson
| Click Here for: | QB | WR | FLEX | TE | D/ST |
| RB | Team | Opponent | |
| 1 | David Johnson | ARI | WSH |
| 2 | Le’Veon Bell | PIT | NYG |
| 3 | LeSean McCoy | BUF | at OAK |
| 4 | Melvin Gordon | SD | TB |
| 5 | Ezekiel Elliott | DAL | at MIN |
| 6 | Jordan Howard | CHI | SF |
| 7 | Theo Riddick | DET | at NO |
| 8 | Matt Forte | NYJ | IND |
| 9 | Mark Ingram | NO | DET |
| 10 | Spencer Ware | KC | at ATL |
| 11 | Devonta Freeman | ATL | KC |
| 12 | Doug Martin | TB | at SD |
| 13 | Jay Ajayi | MIA | at BAL |
| 14 | Latavius Murray | OAK | BUF |
| 15 | Devontae Booker | DEN | at JAX |
| 16 | Frank Gore | IND | at NYJ |
| 17 | Lamar Miller | HOU | at GB |
| 18 | Rashad Jennings | NYG | at PIT |
| 19 | Jeremy Hill | CIN | PHI |
| 20 | LeGarrette Blount | NE | LA |
| 21 | Thomas Rawls | SEA | CAR |
| 22 | Carlos Hyde | SF | at CHI |
| 23 | Jonathan Stewart | CAR | at SEA |
| 24 | Wendell Smallwood | PHI | at CIN |
| 25 | Todd Gurley | LA | at NE |
| 26 | Tim Hightower | NO | DET |
| 27 | Robert Kelley | WSH | at ARI |
| 28 | Matt Asiata | MIN | DAL |
| 29 | Tevin Coleman | ATL | KC |
| 30 | Darren Sproles | PHI | at CIN |
| 31 | Kenneth Dixon | BAL | MIA |
| 32 | Chris Ivory | JAX | DEN |
| 33 | James Starks | GB | HOU |
| 34 | T.J. Yeldon | JAX | DEN |
| 35 | Terrance West | BAL | MIA |
| 36 | Dion Lewis | NE | LA |
| 37 | Rex Burkhead | CIN | PHI |
| 38 | Jerrick McKinnon | MIN | DAL |
| 39 | Paul Perkins | NYG | at PIT |
| 40 | Chris Thompson | WSH | at ARI |
| 41 | James White | NE | LA |
| 42 | Bilal Powell | NYJ | IND |
| 43 | Charcandrick West | KC | at ATL |
| 44 | Ty Montgomery | GB | HOU |
| 45 | Jalen Richard | OAK | BUF |
** Bye Weeks: Browns & Titans **