By The Hudsonian, Joshua Hudson
| Click Here for: | QB | WR | FLEX | TE | D/ST |
| RB | Team | Opponent | |
| 1 | DeMarco Murray | TEN | at IND |
| 2 | Le’Veon Bell | PIT | at CLE |
| 3 | LeSean McCoy | BUF | at CIN |
| 4 | David Johnson | ARI | at MIN |
| 5 | LeGarrette Blount | NE | at SF |
| 6 | Ezekiel Elliott | DAL | BAL |
| 7 | Spencer Ware | KC | TB |
| 8 | Jay Ajayi | MIA | at LA |
| 9 | Theo Riddick | DET | JAX |
| 10 | Jonathan Stewart | CAR | NO |
| 11 | Frank Gore | IND | TEN |
| 12 | C.J. Prosise | SEA | PHI |
| 13 | Isaiah Crowell | CLE | PIT |
| 14 | Lamar Miller | HOU | at OAK |
| 15 | Doug Martin | TB | at KC |
| 16 | Carlos Hyde | SF | NE |
| 17 | Giovani Bernard | CIN | BUF |
| 18 | Jordan Howard | CHI | at NYG |
| 19 | Latavius Murray | OAK | HOU |
| 20 | Todd Gurley | LA | MIA |
| 21 | Duke Johnson Jr. | CLE | PIT |
| 22 | Rashad Jennings | NYG | CHI |
| 23 | James White | NE | at SF |
| 24 | T.J. Yeldon | JAX | at DET |
| 25 | Jeremy Hill | CIN | BUF |
| 26 | Robert Kelley | WSH | GB |
| 27 | Ryan Mathews | PHI | at SEA |
| 28 | Mark Ingram | NO | at CAR |
| 29 | Darren Sproles | PHI | at SEA |
| 30 | Kenneth Dixon | BAL | at DAL |
| 31 | Chris Ivory | JAX | at DET |
| 32 | James Starks | GB | at WSH |
| 33 | Paul Perkins | NYG | CHI |
| 34 | Terrance West | BAL | at DAL |
| 35 | Chris Thompson | WSH | GB |
| 36 | Tim Hightower | NO | at CAR |
| 37 | Jalen Richard | OAK | HOU |
| 38 | Matt Asiata | MIN | ARI |
| 39 | Jerrick McKinnon | MIN | ARI |
| 40 | Thomas Rawls | SEA | PHI |
| 41 | Dwayne Washington | DET | JAX |
| 42 | Ty Montgomery | GB | at WSH |
| 43 | DeAndre Washington | OAK | HOU |
| 44 | Jeremy Langford | CHI | at NYG |
| 45 | Travaris Cadet | NO | at CAR |
** Bye Weeks: Broncos, Chargers, Falcons & Jets **