By The Hudsonian, Joshua Hudson
| Click Here for: | RB | WR | TE | FLEX | D/ST |
| Player | Team | Opponent | |
| 1 | Patrick Mahomes | KC | LAC |
| 2 | Jared Goff | LAR | PHI |
| 3 | Ben Roethlisberger | PIT | NE |
| 4 | Russell Wilson | SEA | @ SF |
| 5 | Andrew Luck | IND | DAL |
| 6 | Drew Brees | NO | @ CAR |
| 7 | Philip Rivers | LAC | @ KC |
| 8 | Cam Newton | CAR | NO |
| 9 | Deshaun Watson | HOU | @ NYJ |
| 10 | Josh Allen | BUF | DET |
| 11 | Tom Brady | NE | @ PIT |
| 12 | Matt Ryan | ATL | ARI |
| 13 | Mitchell Trubisky | CHI | GB |
| 14 | Dak Prescott | DAL | @ IND |
| 15 | Carson Wentz* | PHI | @ LAR |
| 16 | Ryan Tannehill | MIA | @ MIN |
| 17 | Lamar Jackson | BAL | TB |
| 18 | Kirk Cousins | MIN | MIA |
| 19 | Baker Mayfield | CLE | @ DEN |
| 20 | Aaron Rodgers | GB | @ CHI |
| 21 | Derek Carr | OAK | @ CIN |
| 22 | Eli Manning | NYG | TEN |
| 23 | Jameis Winston | TB | @ BAL |
| 24 | Jeff Driskel | CIN | OAK |
| 25 | Marcus Mariota | TEN | @ NYG |
| 26 | Nick Mullens | SF | SEA |
| 27 | Case Keenum | DEN | CLE |
| 28 | Matthew Stafford | DET | @ BUF |
| 29 | Josh Johnson | WAS | @ JAX |
| 30 | Sam Darnold | NYJ | HOU |
| 31 | Cody Kessler | JAX | WAS |
| 32 | Josh Rosen | ARI | @ ATL |