By The Hudsonian, Joshua Hudson
| Click Here for: | RB | WR | TE | FLEX | D/ST |
| Player | Team | Opponent | |
| 1 | Patrick Mahomes | KC | BAL |
| 2 | Philip Rivers | LAC | CIN |
| 3 | Andrew Luck | IND | @ HOU |
| 4 | Aaron Rodgers | GB | ATL |
| 5 | Drew Brees | NO | @ TB |
| 6 | Ben Roethlisberger | PIT | @ OAK |
| 7 | Cam Newton | CAR | @ CLE |
| 8 | Jameis Winston | TB | NO |
| 9 | Russell Wilson | SEA | MIN |
| 10 | Baker Mayfield | CLE | CAR |
| 11 | Jared Goff | LAR | @ CHI |
| 12 | Josh Allen | BUF | NYJ |
| 13 | Deshaun Watson | HOU | IND |
| 14 | Mitchell Trubisky | CHI | LAR |
| 15 | Kirk Cousins | MIN | @ SEA |
| 16 | Tom Brady | NE | @ MIA |
| 17 | Lamar Jackson | BAL | @ KC |
| 18 | Carson Wentz | PHI | @ DAL |
| 19 | Derek Carr | OAK | PIT |
| 20 | Matt Ryan | ATL | @ GB |
| 21 | Marcus Mariota | TEN | JAX |
| 22 | Matthew Stafford | DET | @ ARI |
| 23 | Eli Manning | NYG | @ WAS |
| 24 | Dak Prescott | DAL | PHI |
| 25 | Ryan Tannehill | MIA | NE |
| 26 | Case Keenum | DEN | @ SF |
| 27 | Nick Mullens | SF | DEN |
| 28 | Jeff Driskel | CIN | @ LAC |
| 29 | Josh Rosen | ARI | DET |
| 30 | Josh McCown | NYJ | @ BUF |
| 31 | Mark Sanchez | WAS | NYG |
| 32 | Cody Kessler | JAX | @ TEN |