By The Hudsonian, Joshua Hudson
| Click Here for: | QB | WR | FLEX | TE | D/ST |
| Player | Team | Opponent | |
| 1 | Le’Veon Bell | PIT | @DET |
| 2 | Melvin Gordon | LAC | @NE |
| 3 | LeSean McCoy | BUF | OAK |
| 4 | Devonta Freeman | ATL | NYJ |
| 5 | Ezekiel Elliott | DAL | @WSH |
| 6 | Jordan Howard | CHI | @NO |
| 7 | Chris Thompson | WSH | DAL |
| 8 | Christian McCaffrey | CAR | @TB |
| 9 | Mark Ingram | NO | CHI |
| 10 | Kareem Hunt | KC | DEN |
| 11 | Jay Ajayi | MIA | @BAL |
| 12 | Joe Mixon | CIN | IND |
| 13 | Alvin Kamara | NO | CHI |
| 14 | Wendell Smallwood | PHI | SF |
| 15 | C.J. Anderson | DEN | @KC |
| 16 | Bilal Powell | NYJ | @ATL |
| 17 | James White | NE | LAC |
| 18 | Javorius Allen | BAL | MIA |
| 19 | Carlos Hyde | SF | @PHI |
| 20 | LeGarrette Blount | PHI | SF |
| 21 | Lamar Miller | HOU | @SEA |
| 22 | Doug Martin | TB | CAR |
| 23 | Ameer Abdullah | DET | PIT |
| 24 | Tevin Coleman | ATL | @NYJ |
| 25 | Dion Lewis | NE | LAC |
| 26 | Jerick McKinnon | MIN | @CLE |
| 27 | DeAndre Washington | OAK | @BUF |
| 28 | Duke Johnson Jr. | CLE | MIN |
| 29 | Theo Riddick | DET | PIT |
| 30 | Marlon Mack | IND | @CIN |
| 31 | Rob Kelley | WSH | DAL |
| 32 | Latavius Murray | MIN | @CLE |
| 33 | Tarik Cohen | CHI | @NO |
| 34 | Giovani Bernard | CIN | IND |
| 35 | Matt Forte | NYJ | @ATL |
| 36 | Jonathan Stewart | CAR | @TB |
| 37 | Jalen Richard | OAK | @BUF |
| 38 | Charles Sims | TB | CAR |
| 39 | Frank Gore | IND | @CIN |
| 40 | Mike Gillislee | NE | LAC |
| 41 | Isaiah Crowell | CLE | MIN |
| 42 | Eddie Lacy | SEA | HOU |
| 43 | Austin Ekeler | LAC | @NE |
| 44 | Thomas Rawls | SEA | HOU |
| 45 | Corey Clement | PHI | SF |
| 46 | Devontae Booker | DEN | @KC |
| 47 | D’Onta Foreman | HOU | @SEA |
| 48 | Mike Tolbert | BUF | OAK |
| 49 | Matt Breida | SF | @PHI |
| 50 | Kenyan Drake | MIA | @BAL |
** Week 8 byes: Cardinals, Giants, Jaguars, Packers, Rams, & Titans