By The Hudsonian, Joshua Hudson
| Click Here for: | QB | WR | FLEX | TE | D/ST |
| RB | Team | Opponent | |
| 1 | David Johnson | ARI | at ATL |
| 2 | Le’Veon Bell | PIT | at IND |
| 3 | Jay Ajayi | MIA | SF |
| 4 | Melvin Gordon | SD | at HOU |
| 5 | Ezekiel Elliott | DAL | WSH |
| 6 | DeMarco Murray | TEN | at CHI |
| 7 | LeSean McCoy | BUF | JAX |
| 8 | Rashad Jennings | NYG | at CLE |
| 9 | Frank Gore | IND | PIT |
| 10 | Devonta Freeman | ATL | ARI |
| 11 | Todd Gurley | LA | at NO |
| 12 | Lamar Miller | HOU | SD |
| 13 | Matt Forte | NYJ | NE |
| 14 | Spencer Ware | KC | at DEN |
| 15 | Thomas Rawls | SEA | at TB |
| 16 | Theo Riddick | DET | MIN |
| 17 | Jordan Howard | CHI | TEN |
| 18 | Doug Martin | TB | SEA |
| 19 | Carlos Hyde | SF | at MIA |
| 20 | LeGarrette Blount | NE | at NYJ |
| 21 | Isaiah Crowell | CLE | NYG |
| 22 | Latavius Murray | OAK | CAR |
| 23 | Duke Johnson Jr. | CLE | NYG |
| 24 | Tim Hightower | NO | LA |
| 25 | Robert Kelley | WSH | at DAL |
| 26 | Mark Ingram | NO | LA |
| 27 | Terrance West | BAL | CIN |
| 28 | Darren Sproles | PHI | GB |
| 29 | Devontae Booker | DEN | KC |
| 30 | Ryan Mathews | PHI | GB |
| 31 | Jeremy Hill | CIN | at BAL |
| 32 | Jonathan Stewart | CAR | at OAK |
| 33 | James White | NE | at NYJ |
| 34 | Tevin Coleman | ATL | ARI |
| 35 | James Starks | GB | at PHI |
| 36 | Matt Asiata | MIN | at DET |
| 37 | Jerrick McKinnon | MIN | at DET |
| 38 | Wendell Smallwood | PHI | GB |
| 39 | Kenneth Dixon | BAL | CIN |
| 40 | Chris Ivory | JAX | at BUF |
| 41 | T.J. Yeldon | JAX | at BUF |
| 42 | Chris Thompson | WSH | at DAL |
| 43 | Rex Burkhead | CIN | at BAL |
| 44 | Paul Perkins | NYG | at CLE |
| 45 | Bilal Powell | NYJ | NE |