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Fantasy Football Matchup Report: Starts and Sits for Week 5

Fantasy Football 2025

Club Fantasy’s Weekly Fantasy Football Matchup Report is here to help you set winning lineups. Each week, we spotlight the ten defenses allowing the most points to QBs, RBs, WRs, and TEs, along with the five toughest matchups. Starting this week, our data will reflect each team’s performance over the last three games, rather than season-long statistics. This gives you a clearer, more actionable picture of which matchups to target or avoid based on recent performance. Use this info to guide your start/sit decisions or build a DFS lineup that can win the slate.

Here are the matchups to target and fade for NFL Week 5.

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Week 5 Fantasy Football Matchups

Scoring Note: These rankings use the full PPR scoring format. However, there is not a big difference between the rankings in .5 or non-PPR scoring.

Quarterback Matchups

Most Points Allowed Last 3 Weeks (Matchups to Target)

  1. DAL: plays @ NYJ, consider Justin Fields
  2. MIA: plays @ CAR, consider Bryce Young
  3. NO: plays NYG, consider Jaxson Dart
  4. WAS: plays @ LAC, consider Justin Herbert
  5. CIN: plays DET, consider Jared Goff
  6. IND: plays LV, consider Geno Smith
  7. PIT: BYE
  8. BAL: plays HOU, consider C.J. Stroud
  9. PHI: plays DEN, consider Bo Nix
  10. LV: plays @ IND, consider Daniel Jones

Fewest Points Allowed Last 3 Weeks (Matchups to Fade)

  1. MIN: plays @ CLE, fade Dillon Gabriel
  2. ATL: BYE
  3. KC: plays @ JAX, fade Trevor Lawrence
  4. HOU: plays @ BAL, fade Lamar Jackson and Cooper Rush
  5. SEA: plays TB, fade Baker Mayfield

Running Back Matchups

Most Points Allowed Last 3 Weeks (Matchups to Target)

  1. BAL: plays HOU, consider Nick Chubb and Woody Marks
  2. CHI: BYE
  3. CIN: plays DET, consider Jahmyr Gibbs and David Montgomery
  4. TEN: plays @ ARI, consider Emari Demercado and Michael Carter
  5. KC: plays @ JAX, consider Travis Etienne and Bhayshul Tuten
  6. DAL: plays @ NYJ, consider Breece Hall and Isaiah Davis
  7. NYG: plays @ NO, consider Alvin Kamara and Kendre Miller
  8. ARI: plays TEN, consider Tony Pollard and Tyjae Spears
  9. MIN: plays @ CLE, consider Quinshon Judkins
  10. MIA: plays @ CAR, consider Chuba Hubbard and Rico Dowdle

Fewest Points Allowed Last 3 Weeks (Matchups to Fade)

  1. LAR: plays SF, fade Christian McCaffrey
  2. CLE: plays MIN, fade Jordan Mason and Zavier Scott
  3. ATL: BYE
  4. LAC: plays WAS, fade Bill Croskey-Merritt, Chris Rodriguez, and Jeremy McNichols
  5. GB: BYE

Wide Receiver Matchups

Most Points Allowed Last 3 Weeks (Matchups to Target)

  1. DAL: plays @ NYJ, consider Garrett Wilson
  2. IND: plays LV, consider Jakobi Meyers and Tre Tucker
  3. NYG: plays @ NO, consider Chris Olave and Rashid Shaheed
  4. TEN: plays @ ARI, consider Marvin Harrison Jr.
  5. LV: plays @ IND, consider Michael Pittman Jr.
  6. JAX: plays KC, consider Xavier Worthy, JuJu Smith-Schuster, and Hollywood Brown
  7. WAS: plays @ LAC, consider Quentin Johnston, Keenan Allen, and Ladd McConkey
  8. LAR: plays SF, consider Ricky Pearsall and Jauan Jennings
  9. PIT: BYE
  10. CIN: plays DET, consider Amon-Ra St. Brown and Jameson Williams

Fewest Points Allowed Last 3 Weeks (Matchups to Fade)

  1. MIN: plays @ CLE, fade Jerry Jeudy and Isaiah Bond
  2. KC: plays @ JAX, fade Brian Thomas Jr. and Travis Hunter
  3. LAC: plays WAS, fade Terry McLaurin and Deebo Samuel
  4. CAR: plays MIA, fade Jaylen Waddle
  5. BUF: plays NE, fade Stefon Diggs and Kayshon Boutte

Tight End Matchups

Most Points Allowed Last 3 Weeks (Matchups to Target)

  1. SF: plays @ LAR, consider Tyler Higbee or Davis Allen
  2. PIT: BYE
  3. WAS: plays @ LAC, consider Oronde Gadsden
  4. GB: BYE
  5. CHI: BYE
  6. MIA: plays @ CAR, consider Ja’Tavion Sanders or Tommy Tremble
  7. SEA: plays TB, consider Cade Otton
  8. CAR: plays MIA, consider Darren Waller
  9. DET: plays @ CIN, consider Mike Gesicki
  10. CIN: plays DET, consider Sam LaPorta

Fewest Points Allowed Last 3 Weeks (Matchups to Fade)

  1. ATL: BYE
  2. LV: plays @ IND, fade Tyler Warren
  3. PHI: plays DEN, fade Evan Engram
  4. KC: plays @ JAX, fade Brenton Strange
  5. BUF: plays NE, fade Hunter Henry

Are you looking for more help with NFL Week 5?

Here are Club Fantasy’s Week 5 rankings! Also, you’ll find the rest of our fantasy football articles here!

Finally, don’t forget to tune into our YouTube channel every Wednesday at 8 pm EST for No Punt Intended. Josh, Joe, and Ryan will help get you ready for your Week 5 fantasy matchups!


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