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Fantasy Football Matchup Report: Starts and Sits for Week 4

Fantasy Football 2025

Club Fantasy’s Weekly Fantasy Football Matchup Report is here to help you set winning lineups. Each week, we highlight the ten defenses allowing the most points to QBs, RBs, WRs, and TEs, along with the five toughest matchups. Use this data to guide your start/sit decisions or build a DFS lineup that can win the slate. Here are the matchups to target and avoid for NFL Week 4.

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Week 4 Fantasy Football Matchups

Scoring Note: These rankings use the full PPR scoring format. However, there is not a big difference between the rankings in .5 or non-PPR scoring.

Quarterback Matchups

Most Points Allowed Last 3 Weeks (Matchups to Target)

  1. DAL: plays GB, consider Jordan Love
  2. MIA: plays NYJ, consider Justin Fields or Tyrod Taylor
  3. BAL: plays @ KC, consider Patrick Mahomes
  4. PIT: plays MIN, consider Carson Wentz
  5. CHI: plays @ LV, consider Geno Smith
  6. DET: plays CLE, consider Joe Flacco
  7. NO: plays @ BUF, consider Josh Allen
  8. LV: plays CHI, consider Caleb Williams
  9. TB: plays PHI, consider Jalen Hurts
  10. BUF: plays NO, consider Spencer Rattler or Tyler Shough

Fewest Points Allowed Last 3 Weeks (Matchups to Fade)

  1. CAR: plays @ NE, fade Drake Maye
  2. GB: plays @ DAL, fade Dak Prescott
  3. MIN: plays @ PIT, fade Aaron Rodgers
  4. SEA: plays @ ARI, fade Kyler Murray
  5. IND: plays @ LAR, fade Matthew Stafford

Running Back Matchups

Most Points Allowed Last 3 Weeks (Matchups to Target)

  1. BAL: plays @ KC, consider Isiah Pacheco and Kareem Hunt
  2. CIN: plays @ DEN, consider JK Dobbins and RJ Harvey
  3. TEN: plays @ HOU, consider Nick Chubb and Woody Marks
  4. CHI: plays @ LV, consider Ashton Jeanty
  5. NYG: plays LAC, consider Omarion Hampton
  6. NO: plays @ BUF, consider James Cook
  7. ARI: plays SEA, consider Kenneth Walker and Zach Charbonnet
  8. HOU: plays TEN, consider Tony Pollard
  9. MIA: plays NYJ, consider Breece Hall and Braelon Allen
  10. SEA: plays @ ARI, consider Trey Benson

Fewest Points Allowed Last 3 Weeks (Matchups to Fade)

  1. LAR: plays IND, fade Jonathan Taylor
  2. CLE: plays @ DET, fade Jahmyr Gibbs and David Montgomery
  3. WAS: plays @ ATL, fade Bijan Robinson and Tyler Allgeier
  4. JAX: plays @ SF, fade Christian McCaffrey
  5. LAC: plays @ NYG, fade Cam Skattebo

Wide Receiver Matchups

Most Points Allowed Last 3 Weeks (Matchups to Target)

  1. DAL: plays GB, consider Matthew Golden and Romeo Doubs
  2. NYG: plays LAC, consider Ladd McConkey, Quentin Johnston, and Keenan Allen
  3. TEN: plays @ HOU, consider Nico Collins and Christian Kirk
  4. LV: plays CHI, consider Rome Odunze, DJ Moore, and Luther Burden
  5. CHI: plays @ LV, consider Jakobi Meyers and Tre Tucker
  6. JAX: plays @ SF, consider Ricky Pearsall and Jauan Jennings
  7. WAS: plays @ ATL, consider Drake London and Darnell Mooney
  8. ARI: plays SEA, consider Jaxon Smith-Njigba, Tory Horton, and Cooper Kupp
  9. NE: plays CAR, consider Tetairoa McMillan
  10. DET: plays CLE, consider Cedric Tillman and Jerry Jeudy

Fewest Points Allowed Last 3 Weeks (Matchups to Fade)

  1. MIN: plays @ PIT, fade DK Metcalf and Calvin Austin
  2. SEA: plays @ ARI, fade Marvin Harrison Jr
  3. CAR: plays @ NE, fade Kayshon Boutee and Stefon Diggs
  4. GB: plays @ DAL, fade George Pickens and Jalen Tolbert
  5. ATL: plays WAS, fade Terry McLaurin and Deebo Samuel

Tight End Matchups

Most Points Allowed Last 3 Weeks (Matchups to Target)

  1. SEA: plays @ ARI, consider Trey McBride
  2. PIT: plays MIN, consider TJ Hockenson
  3. MIA: plays NYJ, consider Mason Taylor
  4. CIN: plays @ DEN, consider Evan Engram or Adam Trautman
  5. GB: plays @ DAL, consider Jake Ferguson
  6. DET: plays CLE, consider David Njoku and Harold Fannin
  7. BAL: plays @ KC, consider Travis Kelce
  8. CHI: plays @ LV, consider Brock Bowers
  9. CAR: plays @ NE, consider Hunter Henry
  10. WAS: plays @ ATL, consider Kyle Pitts

Fewest Points Allowed Last 3 Weeks (Matchups to Fade)

  1. ATL: plays WAS, fade Zach Ertz
  2. BUF: plays NO, fade Juwan Johnson
  3. KC: plays BAL, fade Mark Andrews and Isaiah Likely
  4. PHI: plays @ TB, fade Cade Otton
  5. LV: plays CHI, fade Colston Loveland and Cole Kmet

Are you looking for more help with NFL Week 4?

Here are Club Fantasy’s Week 4 rankings! Also, you’ll find the rest of our fantasy football articles here!

Finally, don’t forget to tune into our YouTube channel every Wednesday at 8 pm EST for No Punt Intended. Josh, Joe, and Ryan will help get you ready for your Week 2 fantasy matchups!


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