Our Weekly Matchup Report is here to help you build the best possible lineups. Each week, we list the ten teams that have the best matchups for QB/RB/WR/TE and the five that have the worst matchups. This list shows how defenses rank over the last FIVE weeks. I used to list the season-long rankings in this report, but your host site already gives you that info. The fact is, as the season progresses, defenses can get better or worse. So, focusing on the most recent five games could be more relevant information for making your Start-Sit Decisions or building a team to win a DFS slate! With all of that said, here are the matchups to target or avoid in NFL Week 15.
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NFL Matchup Report: Week 16
Scoring Note: These rankings use the full PPR scoring format. However, there is not a big difference between the rankings in .5 or non-PPR scoring. These are the best and worst matchups since Week 10.
Quarterbacks
| Points Allowed Last 5 Weeks |
Team | Week 16 Opponent |
| Most | JAX | @ LV |
| 2 | NE | @ BUF |
| 3 | CAR | vs ARI |
| 4 | LAR | @ NYJ |
| 5 | NYJ | vs LAR |
| 6 | NYG | @ ATL |
| 7 | BUF | vs NE |
| 8 | CIN | vs CLE |
| 9 | ATL | vs NYG |
| 10 | DET | @ CHI |
| Bottom 5 | ||
| 28 | SEA | vs MIN |
| 29 | GB | vs NO |
| 30 | HOU | @ KC |
| 31 | IND | vs TEN |
| Least | BAL | vs PIT |
Consider Starting These Players
Aidan O’Connell or Desmond Ridder | Josh Allen | Kyler Murray | Aaron Rodgers | Matthew Stafford | Michael Penix | Drake Maye | Dorian Thompson-Robinson | Tim Boyle or Tommy DeVito | Caleb Williams
Consider Fading These Players
Sam Darnold | Spencer Rattler | Patrick Mahomes and Carson Wentz | Mason Rudolph | Russell Wilson
Running Backs
| Points Allowed Last 5 Weeks |
Team | Week 16 Opponent |
| Most | NYG | @ ATL |
| 2 | CIN | vs CLE |
| 3 | CHI | vs DET |
| 4 | IND | vs TEN |
| 5 | JAX | @ LV |
| 6 | GB | vs NO |
| 7 | BUF | vs NE |
| 8 | LAC | vs DEN |
| 9 | LAR | @ NYJ |
| 10 | ARI | @ CAR |
| Bottom 5 | ||
| 28 | NO | @ GB |
| 29 | DEN | @ LAC |
| 30 | NYJ | vs LAR |
| 31 | MIN | @ SEA |
| Least | TB | @ DAL |
Consider Starting These Players
Bijan Robinson and Tyler Allgeier | Jerome Ford and D’Onta Foreman | Jahmyr Gibbs | Tony Pollard and Tyjae Spears | Alexander Mattison and Ameer Abdullah | Alvin Kamara and Kendre Miller | Rhamondre Stevenson and Antonio Gibson | Javonte Williams, Jaleel McLaughlin, and Audric Estime | Breece Hall, Braelon Allen, and Isaiah Davis | Chuba Hubbard
Consider Fading These Players
Josh Jacobs | Gus Edwards and Kimani Vidal | Kyren Williams and Blake Corum | Kenneth Walker and Zach Charbonnet | Rico Dowdle and Ezekiel Elliott
Wide Receivers
| Points Allowed Last 5 Weeks |
Team | Week 16 Opponent |
| Most | BUF | vs NE |
| 2 | ATL | vs NYG |
| 3 | JAX | @ LV |
| 4 | MIN | @ SEA |
| 5 | LAC | vs DEN |
| 6 | NYJ | vs LAR |
| 7 | NO | @ GB |
| 8 | DEN | @ LAC |
| 9 | DAL | vs TB |
| 10 | LV | vs JAX |
| Bottom 5 | ||
| 28 | SEA | vs MIN |
| 29 | WAS | vs PHI |
| 30 | PHI | @ WAS |
| 31 | IND | vs TEN |
| Least | BAL | vs PIT |
Consider Starting These Players
Demario Douglas, Kayshon Boutte, and Kendrick Bourne | Malik Nabers and Wan’Dale Robinson | Jakobi Meyers and Tre Tucker | D.K. Metcalf and Jaxon Smith-Njigba | Courtland Sutton, Marvin Mims, and Devaughn Vele | Puka Nacua and Cooper Kupp | Jayden Reed, Romeo Doubs, and Christian Watson | Ladd McConkey, Quentin Johnston, and Josh Palmer | Mike Evans and Jalen McMillan | Brian Thomas and Parker Washington
Consider Fading These Players
Justin Jefferson and Jordan Addison | A.J. Brown and DeVonta Smith | Terry McLaurin and Noah Brown | Calvin Ridley and Nick Westbrook-Ikhine | George Pickens and Calvin Austin
Tight Ends
| Points Allowed Last 5 Weeks |
Team | Week 16 Opponent |
| Most | CLE | @ CIN |
| 2 | CIN | vs CLE |
| 3 | HOU | @ KC |
| 4 | IND | vs TEN |
| 5 | NE | @ BUF |
| 6 | MIA | vs SF |
| 7 | LV | vs JAX |
| 8 | PHI | @ WAS |
| 9 | CAR | vs ARI |
| 10 | PIT | @ BAL |
| Bottom 5 | ||
| 28 | BAL | vs PIT |
| 29 | DET | @ CHI |
| 30 | LAC | vs DEN |
| 31 | ATL | vs NYG |
| Least | SF | @ MIA |
Consider Starting These Players
Mike Gesicki | David Njoku or Jordan Akins | Travis Kelce | Chigoziem Okonkwo | Dalton Kincaid | George Kittle | Brenton Strange | Zach Ertz or Ben Sinnott | Trey McBride | Mark Andrews
Consider Fading These Players
Pat Freiermuth | Cole Kmet | Adam Trautman | Daniel Bellinger | Jonnu Smith
Are you looking for more help with NFL Week 16?
Here are Club Fantasy’s Week 16 rankings! Also, you’ll find the rest of our Week 16 content here!
Finally, don’t forget to tune into our YouTube channel every Wednesday at 8 pm EST for No Punt Intended. Josh, Joe, and Ryan will help get you ready for your NFL Week 16 fantasy matchups!
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