By The Hudsonian, Joshua Hudson
| Click Here for: | QB | WR | TE | FLEX | D/ST |
| Player | Team | Opponent | |
| 1 | Todd Gurley II | LAR | @ NO |
| 2 | Kareem Hunt | KC | @ CLE |
| 3 | Alvin Kamara | NO | LAR |
| 4 | Melvin Gordon | LAC | @ SEA |
| 5 | Christian McCaffrey | CAR | TB |
| 6 | James White | NE | GB |
| 7 | Adrian Peterson | WAS | ATL |
| 8 | Lamar Miller | HOU | @ DEN |
| 9 | James Conner | PIT | @ BAL |
| 10 | Ezekiel Elliott | DAL | TEN |
| 11 | Tarik Cohen | CHI | @ BUF |
| 12 | Isaiah Crowell | NYJ | @ MIA |
| 13 | Kenyan Drake | MIA | NYJ |
| 14 | Nick Chubb | CLE | KC |
| 15 | Matt Breida | SF | OAK |
| 16 | Latavius Murray | MIN | DET |
| 17 | Kerryon Johnson | DET | @ MIN |
| 18 | Chris Carson | SEA | LAC |
| 19 | Aaron Jones | GB | @ NE |
| 20 | Tevin Coleman | ATL | @ WAS |
| 21 | Philip Lindsay | DEN | HOU |
| 22 | Mark Ingram | NO | LAR |
| 23 | LeSean McCoy | BUF | CHI |
| 24 | Jordan Howard | CHI | @ BUF |
| 25 | Jalen Richard | OAK | @ SF |
| 26 | Chris Thompson | WAS | ATL |
| 27 | Doug Martin | OAK | @ SF |
| 28 | Dion Lewis | TEN | @ DAL |
| 29 | Duke Johnson Jr. | CLE | KC |
| 30 | Alex Collins | BAL | PIT |
| 31 | Austin Ekeler | LAC | @ SEA |
| 32 | Trenton Cannon | NYJ | @ MIA |
| 33 | Jamaal Williams | GB | @ NE |
| 34 | Devontae Booker | DEN | HOU |
| 35 | Peyton Barber | TB | @ CAR |
| 36 | Frank Gore | MIA | NYJ |
| 37 | Raheem Mostert | SF | OAK |
| 38 | Javorius “Buck” Allen | BAL | PIT |
| 39 | Mike Davis | SEA | LAC |
| 40 | Ito Smith | ATL | @ WAS |
| 41 | Jacquizz Rodgers | TB | @ CAR |
| 42 | Derrick Henry | TEN | @ DAL |
| 43 | Chris Ivory | BUF | CHI |
| 44 | Alfred Blue | HOU | @ DEN |
| 45 | Spencer Ware | KC | @ CLE |
| 46 | Marcus Murphy | BUF | CHI |
| 47 | LeGarrette Blount | DET | @ MIN |
| 48 | Kenjon Barner | NE | GB |
| 49 | Alfred Morris | SF | OAK |
| 50 | Rashaad Penny | SEA | LAC |
** Byes: Bengals, Cardinals, Colts, Eagles, Giants, & Jaguars
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