By The Hudsonian, Joshua Hudson
| Click Here for: | QB | RB | WR | TE | D/ST |
| Player | Team | Opponent | Position | |
| 1 | Saquon Barkley | NYG | @ ATL | RB1 |
| 2 | Todd Gurley II | LAR | @ SF | RB2 |
| 3 | Adam Thielen | MIN | @ NYJ | WR1 |
| 4 | Tyreek Hill | KC | CIN | WR2 |
| 5 | Odell Beckham Jr. | NYG | @ ATL | WR3 |
| 6 | A.J. Green | CIN | @ KC | WR4 |
| 7 | David Johnson | ARI | DEN | RB3 |
| 8 | Melvin Gordon | LAC | TEN | RB4 |
| 9 | Kareem Hunt | KC | CIN | RB5 |
| 10 | Joe Mixon | CIN | @ KC | RB6 |
| 11 | Julio Jones | ATL | NYG | WR5 |
| 12 | DeAndre Hopkins | HOU | @ JAX | WR6 |
| 13 | Michael Thomas | NO | @ BAL | WR7 |
| 14 | Travis Kelce | KC | CIN | TE1 |
| 15 | Zach Ertz | PHI | CAR | TE2 |
| 16 | Ezekiel Elliott | DAL | @ WAS | RB7 |
| 17 | Robert Woods | LAR | @ SF | WR8 |
| 18 | Stefon Diggs | MIN | @ NYJ | WR9 |
| 19 | Mike Evans | TB | CLE | WR10 |
| 20 | Brandin Cooks | LAR | @ SF | WR11 |
| 21 | Mark Ingram | NO | @ BAL | RB8 |
| 22 | Christian McCaffrey | CAR | @ PHI | RB9 |
| 23 | Philip Lindsay | DEN | @ ARI | RB10 |
| 24 | Rob Gronkowski | NE | @ CHI | TE3 |
| 25 | Alvin Kamara | NO | @ BAL | RB11 |
| 26 | Tevin Coleman | ATL | NYG | RB12 |
| 27 | Sony Michel | NE | @ CHI | RB13 |
| 28 | Royce Freeman | DEN | @ ARI | RB14 |
| 29 | Kerryon Johnson | DET | @ MIA | RB15 |
| 30 | Keenan Allen | LAC | TEN | WR12 |
| 31 | Tyler Boyd | CIN | @ KC | WR13 |
| 32 | Alshon Jeffery | PHI | CAR | WR14 |
| 33 | Kenny Golladay | DET | @ MIA | WR15 |
| 34 | Jarvis Landry | CLE | @ TB | WR16 |
| 35 | Emmanuel Sanders | DEN | @ ARI | WR17 |
| 36 | Allen Robinson | CHI | NE | WR18 |
| 37 | Josh Gordon | NE | @ CHI | WR19 |
| 38 | Michael Crabtree | BAL | NO | WR20 |
| 39 | John Brown | BAL | NO | WR21 |
| 40 | Julian Edelman | NE | @ CHI | WR22 |
| 41 | Eric Ebron | IND | BUF | TE4 |
| 42 | T.J. Yeldon | JAX | HOU | RB16 |
| 43 | Tarik Cohen | CHI | NE | RB17 |
| 44 | Carlos Hyde | CLE | @ TB | RB18 |
| 45 | Kenyan Drake | MIA | DET | RB19 |
| 46 | Matt Breida | SF | LAR | RB20 |
| 47 | Taylor Gabriel | CHI | NE | WR23 |
| 48 | Mohamed Sanu | ATL | NYG | WR24 |
| 49 | David Njoku | CLE | @ TB | TE5 |
| 50 | LeSean McCoy | BUF | @ IND | RB21 |
| 51 | Adrian Peterson | WAS | DAL | RB22 |
| 52 | Peyton Barber | TB | CLE | RB23 |
| 53 | Duke Johnson Jr. | CLE | @ TB | RB24 |
| 54 | Golden Tate | DET | @ MIA | WR25 |
| 55 | Devin Funchess | CAR | @ PHI | WR26 |
| 56 | Marvin Jones Jr. | DET | @ MIA | WR27 |
| 57 | Sterling Shepard | NYG | @ ATL | WR28 |
| 58 | DeSean Jackson | TB | CLE | WR29 |
| 59 | Evan Engram | NYG | @ ATL | TE6 |
| 60 | Latavius Murray | MIN | @ NYJ | RB25 |
| 61 | Frank Gore | MIA | DET | RB26 |
| 62 | Isaiah Crowell | NYJ | MIN | RB27 |
| 63 | James White | NE | @ CHI | RB28 |
| 64 | Ito Smith | ATL | NYG | RB29 |
| 65 | Austin Hooper | ATL | NYG | TE7 |
| 66 | Corey Davis | TEN | @ LAC | WR30 |
| 67 | Demaryius Thomas | DEN | @ ARI | WR31 |
| 68 | Dion Lewis | TEN | @ LAC | RB30 |
| 69 | Jordan Howard | CHI | NE | RB31 |
| 70 | Chris Thompson | WAS | DAL | RB32 |
| 71 | Wendell Smallwood | PHI | CAR | RB33 |
| 72 | Bilal Powell | NYJ | MIN | RB34 |
| 73 | Corey Clement | PHI | CAR | RB35 |
| 74 | Willie Snead IV | BAL | NO | WR32 |
| 75 | Christian Kirk | ARI | DEN | WR33 |
| 76 | Sammy Watkins | KC | CIN | WR34 |
| 77 | Jermaine Kearse | NYJ | MIN | WR35 |
| 78 | Dede Westbrook | JAX | HOU | WR36 |
| 79 | Will Fuller V | HOU | @ JAX | WR37 |
| 80 | George Kittle | SF | LAR | TE8 |
| 81 | C.J. Uzomah | CIN | @ KC | TE9 |
| 82 | Chris Godwin | TB | CLE | WR38 |
| 83 | Chris Hogan | NE | @ CHI | WR39 |
| 84 | Nelson Agholor | PHI | CAR | WR40 |
| 85 | Cole Beasley | DAL | @ WAS | WR41 |
| 86 | Albert Wilson | MIA | DET | WR42 |
| 87 | Greg Olsen | CAR | @ PHI | TE10 |
| 88 | Jordan Reed | WAS | DAL | TE11 |
| 89 | O.J. Howard | TB | CLE | TE12 |
| 90 | Javorius “Buck” Allen | BAL | NO | RB36 |
| 91 | Nyheim Hines | IND | BUF | RB37 |
| 92 | Alex Collins | BAL | NO | RB38 |
| 93 | Marlon Mack | IND | BUF | RB39 |
| 94 | Lamar Miller | HOU | @ JAX | RB40 |
| 95 | Austin Ekeler | LAC | TEN | RB41 |
| 96 | Keke Coutee | HOU | @ JAX | WR43 |
| 97 | Keelan Cole | JAX | HOU | WR44 |
| 98 | Marquise Goodwin | SF | LAR | WR45 |
| 99 | Antonio Callaway | CLE | @ TB | WR46 |
| 100 | Calvin Ridley | ATL | NYG | WR47 |
| 101 | Alfred Morris | SF | LAR | RB42 |
| 102 | Kyle Rudolph | MIN | @ NYJ | TE13 |
| 103 | Trey Burton | CHI | NE | TE14 |
| 104 | Ricky Seals-Jones | ARI | DEN | TE15 |
| 105 | Robby Anderson | NYJ | MIN | WR48 |
| 106 | Chester Rogers | IND | BUF | WR49 |
| 107 | Mike Williams | LAC | TEN | WR50 |
| 108 | LeGarrette Blount | DET | @ MIA | RB43 |
| 109 | Alfred Blue | HOU | @ JAX | RB44 |
| 110 | Jamaal Charles | JAX | HOU | RB45 |
| 111 | Ronald Jones II | TB | CLE | RB46 |
| 112 | Raheem Mostart | SF | LAR | RB47 |
| 113 | Devontae Booker | DEN | @ ARI | RB48 |
| 114 | Benjamin Watson | NO | @ BAL | TE16 |
| 115 | Pierre Garcon | SF | LAR | WR51 |
| 116 | Allen Hurns | DAL | @ WAS | WR52 |
| 117 | Danny Amendola | MIA | DET | WR53 |
| 118 | D.J. Moore | CAR | @ PHI | WR54 |
| 119 | Theo Riddick | DET | @ MIA | RB49 |
| 120 | Kelvin Benjamin | BUF | @ IND | WR55 |
| 121 | Tyrell Williams | LAC | TEN | WR56 |
| 122 | Taywan Taylor | TEN | @ LAC | WR57 |
| 123 | Josh Reynolds | LAR | @ SF | WR58 |
| 124 | Kenny Stills | MIA | DET | WR59 |
| 125 | Anthony Miller | CHI | NE | WR60 |
** Bye Weeks: Packers, Raiders, Steelers, & Seahawks