By The Hudsonian, Joshua Hudson
| Click Here for: | QB | WR | TE | FLEX | D/ST |
| Player | Team | Opponent | |
| 1 | James Conner | PIT | @ TB |
| 2 | Todd Gurley II | LAR | LAC |
| 3 | Alvin Kamara | NO | @ ATL |
| 4 | Jordan Howard | CHI | @ ARI |
| 5 | Dalvin Cook | MIN | BUF |
| 6 | Christian McCaffrey | CAR | CIN |
| 7 | Ezekiel Elliott | DAL | @ SEA |
| 8 | Saquon Barkley | NYG | @ HOU |
| 9 | Kareem Hunt | KC | SF |
| 10 | David Johnson | ARI | CHI |
| 11 | Kenyan Drake | MIA | OAK |
| 12 | Leonard Fournette | JAX | TEN |
| 13 | Lamar Miller | HOU | NYG |
| 14 | Tevin Coleman | ATL | NO |
| 15 | Melvin Gordon | LAC | @ LAR |
| 16 | Chris Thompson | WAS | GB |
| 17 | Matt Breida | SF | @ KC |
| 18 | Jay Ajayi | PHI | IND |
| 19 | Marshawn Lynch | OAK | @ MIA |
| 20 | James White | NE | @ DET |
| 21 | Dion Lewis | TEN | @ JAX |
| 22 | Sony Michel | NE | @ DET |
| 23 | Isaiah Crowell | NYJ | @ CLE |
| 24 | Phillip Lindsay | DEN | @ BAL |
| 25 | Javorius “Buck” Allen | BAL | DEN |
| 26 | Giovani Bernard | CIN | @ CAR |
| 27 | Carlos Hyde | CLE | NYJ |
| 28 | Alex Collins | BAL | DEN |
| 29 | Bilal Powell | NYJ | @ CLE |
| 30 | Chris Carson | SEA | DAL |
| 31 | Theo Riddick | DET | NE |
| 32 | Adrian Peterson | WAS | GB |
| 33 | LeSean McCoy | BUF | @ MIN |
| 34 | Tarik Cohen | CHI | @ ARI |
| 35 | Royce Freeman | DEN | @ BAL |
| 36 | Alfred Morris | SF | @ KC |
| 37 | Rashaad Penny | SEA | DAL |
| 38 | Derrick Henry | TEN | @ JAX |
| 39 | Kerryon Johnson | DET | NE |
| 40 | Rex Burkhead | NE | @ DET |
| 41 | Peyton Barber | TB | @ PIT |
| 42 | Austin Ekeler | LAC | @ LAR |
| 43 | Jamaal Williams | GB | @ WAS |
| 44 | Duke Johnson Jr. | CLE | NYJ |
| 45 | Frank Gore | MIA | OAK |
| 46 | Nyheim Hines | IND | @ PHI |
| 47 | Aaron Jones | GB | @ WAS |
| 48 | Corey Clement | PHI | IND |
| 49 | Ito Smith | ATL | NO |
| 50 | C.J. Anderson | CAR | CIN |
| 51 | Jordan Wilkins | IND | @ PHI |
| 52 | T.J. Yeldon | JAX | TEN |
| 53 | Jacquizz Rodgers | TB | PIT |
| 54 | Doug Martin | OAK | @ MIA |
| 55 | Latavius Murray | MIN | BUF |
| 56 | Chris Ivory | BUF | @ MIN |
| 57 | Chase Edmunds | ARI | CHI |
| 58 | Marlon Mack | IND | @ PHI |
| 59 | Mike Gillislee | NO | @ ATL |
| 60 | Ty Montgomery | GB | @ WAS |