By The Hudsonian, Joshua Hudson
| Click Here for: | QB | WR | FLEX | TE | D/ST |
| Player | Team | Opponent | |
| 1 | Le’Veon Bell | PIT | @CIN |
| 2 | Todd Gurley | LAR | @ARI |
| 3 | Leonard Fournette | JAX | IND |
| 4 | Alvin Kamara | NO | CAR |
| 5 | Jordan Howard | CHI | SF |
| 6 | Mark Ingram | NO | CAR |
| 7 | Melvin Gordon | LAC | CLE |
| 8 | LeSean McCoy | BUF | NE |
| 9 | Carlos Hyde | SF | @CHI |
| 10 | Christian McCaffrey | CAR | @NO |
| 11 | Kareem Hunt | KC | @NYJ |
| 12 | Lamar Miller | HOU | @TEN |
| 13 | Alex Collins | BAL | DET |
| 14 | Latavius Murray | MIN | @ATL |
| 15 | Marshawn Lynch | OAK | NYG |
| 16 | Jerick McKinnon | MIN | @ATL |
| 17 | Samaje Perine | WSH | @DAL |
| 18 | DeMarco Murray | TEN | HOU |
| 19 | Devonta Freeman | ATL | MIN |
| 20 | Kenyan Drake | MIA | DEN |
| 21 | Rex Burkhead | NE | @BUF |
| 22 | Duke Johnson Jr. | CLE | @LAC |
| 23 | Adrian Peterson | ARI | LAR |
| 24 | Danny Woodhead | BAL | DET |
| 25 | Devontae Booker | DEN | @MIA |
| 26 | Dion Lewis | NE | @BUF |
| 27 | Isaiah Crowell | CLE | @LAC |
| 28 | Jay Ajayi | PHI | @SEA |
| 29 | Joe Mixon | CIN | PIT |
| 30 | Alfred Morris | DAL | WSH |
| 31 | Jamaal Williams | GB | TB |
| 32 | Orleans Darkwa | NYG | @OAK |
| 33 | Frank Gore | IND | @JAX |
| 34 | Doug Martin | TB | @GB |
| 35 | Ty Montgomery | GB | TB |
| 36 | Matt Forte | NYJ | KC |
| 37 | Austin Ekeler | LAC | CLE |
| 38 | Tevin Coleman | ATL | MIN |
| 39 | Rod Smith | DAL | WSH |
| 40 | Jonathan Stewart | CAR | @NO |
| 41 | Ameer Abdullah | DET | @BAL |
| 42 | LeBarrette Blount | PHI | @SEA |
| 43 | C.J. Anderson | DEN | @MIA |
| 44 | Derrick Henry | TEN | HOU |
| 45 | J.D. McKissic | SEA | PHI |
| 46 | James White | NE | @BUF |
| 47 | DeAndre Washington | OAK | NYG |
| 48 | Wayne Gallman | NYG | @OAK |
| 49 | Mike Davis | SEA | PHI |
| 50 | D.J. Foster | ARI | LAR |