By The Hudsonian, Joshua Hudson
| Click Here for: | QB | WR | FLEX | TE | D/ST |
| Player | Team | Opponent | |
| 1 | Kareem Hunt | KC | @NYG |
| 2 | Melvin Gordon | LAC | BUF |
| 3 | Le’Veon Bell | PIT | TEN |
| 4 | LeSean McCoy | BUF | @LAC |
| 5 | Jordan Howard | CHI | DET |
| 6 | Mark Ingram | NO | WSH |
| 7 | Leonard Fournette | JAX | @CLE |
| 8 | Alvin Kamara | NO | WSH |
| 9 | Todd Gurley | LAR | @MIN |
| 10 | Jerick McKinnon | MIN | LAR |
| 11 | Tevin Coleman | ATL | @SEA |
| 12 | Adrian Peterson | ARI | @HOU |
| 13 | Isaiah Crowell | CLE | JAX |
| 14 | Lamar Miller | HOU | ARI |
| 15 | Latavius Murray | MIN | LAR |
| 16 | Duke Johnson Jr. | CLE | JAX |
| 17 | Chris Thompson | WSH | @NO |
| 18 | Javorius Allen | BAL | @GB |
| 19 | DeMarco Murray | TEN | @PIT |
| 20 | Jamaal Williams | GB | BAL |
| 21 | Jay Ajayi | PHI | @DAL |
| 22 | Joe Mixon | CIN | @DEN |
| 23 | James White | NE | @OAK |
| 24 | Ameer Abdullah | DET | @CHI |
| 25 | Alex Collins | BAL | @GB |
| 26 | Marshawn Lynch | OAK | NE |
| 27 | Kenyan Drake | MIA | TB |
| 28 | Orleans Darkwa | NYG | KC |
| 29 | C.J. Anderson | DEN | CIN |
| 30 | Doug Martin | TB | @MIA |
| 31 | Dion Lewis | NE | @OAK |
| 32 | Damien Williams | MIA | TB |
| 33 | Alfred Morris | DAL | PHI |
| 34 | LeGarrette Blount | PHI | @DAL |
| 35 | Theo Riddick | DET | @CHI |
| 36 | Giovani Bernard | CIN | @DEN |
| 37 | Tarik Cohen | CHI | DET |
| 38 | Rex Burkhead | NE | @OAK |
| 39 | Devontae Booker | DEN | CIN |
| 40 | Samaje Perine | WSH | @NO |
| 41 | Rod Smith | DAL | PHI |
| 42 | Thomas Rawls | SEA | ATL |
| 43 | Andre Ellington | ARI | @HOU |
| 44 | T.J. Yeldon | JAX | @CLE |
| 45 | DeAndre Washington | OAK | NE |
| 46 | Terron Ward | ATL | @SEA |
| 47 | Eddie Lacy | SEA | ATL |
| 48 | Shane Vereen | NYG | KC |
| 49 | Jalen Richard | OAK | NE |
| 50 | Wayne Gallman | NYG | KC |
** Week 11 byes: 49ers, Colts, Jets, & Panthers