By The Hudsonian, Joshua Hudson
| Click Here for: | QB | RB | WR | FLEX | D/ST |
| Player | Team | Opponent | |
| 1 | Zach Ertz | PHI | @CAR |
| 2 | Rob Gronkowski | NE | @NYJ |
| 3 | Delanie Walker | TEN | IND |
| 4 | Evan Engram | NYG | @DEN |
| 5 | Travis Kelce | KC | PIT |
| 6 | Jordan Reed | WSH | SF |
| 7 | Ryan Griffin | HOU | CLE |
| 8 | Austin Sefarian-Jenkins | NYJ | NE |
| 9 | Cameron Brate | TB | @ARI |
| 10 | George Kittle | SF | @WSH |
| 11 | Zach Miller | CHI | @BAL |
| 12 | Hunter Henry | LAC | @OAK |
| 13 | Martellus Bennett | GB | @MIN |
| 14 | Ed Dickson | CAR | PHI |
| 15 | Kyle Rudolph | MIN | GB |
| 16 | Jared Cook | OAK | LAC |
| 17 | David Njoku | CLE | @HOU |
| 18 | Jack Doyle | IND | @TEN |
| 19 | Austin Hooper | ATL | MIA |
| 20 | A.J. Derby | DEN | NYG |
| 21 | Coby Fleener | NO | DET |
| 22 | Benjamin Watson | BAL | CHI |
| 23 | Tyler Higbee | LAR | @JAX |
| 24 | Jesse James | PIT | @KC |
| 25 | Eric Ebron | DET | @NO |
| 26 | Jermaine Gresham | ARI | TB |
| 27 | Julius Thomas | MIA | @ATL |
| 28 | Stephen Anderson | HOU | CLE |
| 29 | Seth DeValve | CLE | @HOU |
| 30 | Antonio Gates | LAC | @OAK |
** Week 6 byes: Bills, Bengals, Cowboys, Seahawks