By The Hudsonian, Joshua Hudson
| Click Here for: | QB | RB | WR | TE | FLEX |
| Player | Opponent | |
| 1 | Jaguars | LAR |
| 2 | Falcons | MIA |
| 3 | Ravens | CHI |
| 4 | Broncos | NYG |
| 5 | Redskins | SF |
| 6 | Chiefs | PIT |
| 7 | Texans | CLE |
| 8 | Titans | IND |
| 9 | Eagles | @CAR |
| 10 | Patriots | @NYJ |
| 11 | Vikings | GB |
| 12 | Bucs | @ARI |
| 13 | Cardinals | TB |
| 14 | Chargers | @OAK |
| 15 | Giants | @DEN |
| 16 | Lions | @NO |
| 17 | Bears | @BAL |
| 18 | Steelers | @KC |
| 19 | Packers | @MIN |
| 20 | Panthers | PHI |
| 21 | Saints | DET |
| 22 | Browns | @HOU |
| 23 | Rams | @JAX |
| 24 | Raiders | LAC |
| 25 | 49ers | @WSH |
| 26 | Colts | @TEN |
| 27 | Dolphins | @ATL |
| 28 | Jets | NE |
** Week 6 byes: Bills, Bengals, Cowboys, Seahawks