By The Hudsonian, Joshua Hudson
| Click Here for: | QB | WR | FLEX | TE | D/ST |
| Player | Team | Opponent | |
| 1 | Ezekiel Elliott | DAL | LAR |
| 2 | LeSean McCoy | BUF | @ATL |
| 3 | Kareem Hunt | KC | WSH |
| 4 | Todd Gurley | LAR | @DAL |
| 5 | Devonta Freeman | ATL | BUF |
| 6 | Dalvin Cook | MIN | DET |
| 7 | Leonard Fournette | JAX | @NYJ |
| 8 | Jay Ajayi | MIA | NO |
| 9 | Le’Veon Bell | PIT | @BAL |
| 10 | Christian McCaffrey | CAR | @NE |
| 11 | Ty Montgomery | GB | CHI |
| 12 | Jordan Howard | CHI | @GB |
| 13 | C.J. Anderson | DEN | OAK |
| 14 | Melvin Gordon | LAC | PHI |
| 15 | Carlos Hyde | SF | @ARI |
| 16 | Chris Thompson | WSH | @KC |
| 17 | Javorius Allen | BAL | PIT |
| 18 | DeMarco Murray | TEN | @HOU |
| 19 | Chris Carson | SEA | IND |
| 20 | Joe Mixon | CIN | @CLE |
| 21 | Mark Ingram | NO | @MIA |
| 22 | Tevin Coleman | ATL | BUF |
| 23 | Tarik Cohen | CHI | @GB |
| 24 | Frank Gore | IND | @SEA |
| 25 | Andre Ellington | ARI | SF |
| 26 | Lamar Miller | HOU | TEN |
| 27 | Wendell Smallwood | PHI | @LAC |
| 28 | Theo Riddick | DET | @MIN |
| 29 | Mike Gillislee | NE | CAR |
| 30 | Duke Johnson Jr. | CLE | CIN |
| 31 | Marshawn Lynch | OAK | @DEN |
| 32 | Jacquizz Rodgers | TB | NYG |
| 33 | Ameer Abdullah | DET | @MIN |
| 34 | LeGarrette Blount | PHI | @LAC |
| 35 | James White | NE | CAR |
| 36 | Alvin Kamara | NO | @MIA |
| 37 | Bilal Powell | NYJ | JAX |
| 38 | Jonathan Stewart | CAR | @NE |
| 39 | Chris Johnson | ARI | SF |
| 40 | Giovani Bernard | CIN | @CLE |
| 41 | Terrance West | BAL | PIT |
| 42 | C.J. Prosise | SEA | IND |
| 43 | Shane Vereen | NYG | @TB |
| 44 | Charles Sims | TB | NYG |
| 45 | Jamaal Charles | DEN | OAK |
| 46 | DeAndre Washington | OAK | @DEN |
| 47 | Derrick Henry | TEN | @HOU |
| 48 | Robert Turbin | IND | @SEA |
| 49 | Paul Perkins | NYG | @TB |
| 50 | Chris Ivory | JAX | @NYJ |
| 51 | Kerwynn Williams | ARI | SF |
| 52 | Adrian Peterson | NO | @MIA |
| 53 | Jerick McKinnon | MIN | DET |
| 54 | Mike Tolbert | BUF | @ATL |
| 55 | Jamaal Williams | GB | CHI |
| 56 | Kenyan Drake | MIA | NO |
| 57 | Jeremy Hill | CIN | @CLE |
| 58 | Matt Breida | SF | @ARI |
| 59 | Corey Clement | PHI | @LAC |
| 60 | Dion Lewis | NE | CAR |