By The Hudsonian, Joshua Hudson
| Click Here for: | QB | WR | FLEX | TE | D/ST |
| RB | Team | Opponent | |
| 1 | DeMarco Murray | TEN | IND |
| 2 | Le’Veon Bell | PIT | NE |
| 3 | Devonta Freeman | ATL | SD |
| 4 | Melvin Gordon | SD | at ATL |
| 5 | David Johnson | ARI | SEA |
| 6 | Spencer Ware | KC | NO |
| 7 | James White | NE | at PIT |
| 8 | LeSean McCoy | BUF | at MIA |
| 9 | Lamar Miller | HOU | at DEN |
| 10 | Jacquizz Rodgers | TB | at SF |
| 11 | Todd Gurley | LA | NYG |
| 12 | Theo Riddick | DET | WSH |
| 13 | C.J. Anderson | DEN | HOU |
| 14 | Mark Ingram | NO | at KC |
| 15 | Giovani Bernard | CIN | CLE |
| 16 | Tevin Coleman | ATL | SD |
| 17 | Jordan Howard | CHI | at GB |
| 18 | Matt Jones | WSH | at DET |
| 19 | Terrance West | BAL | at NYJ |
| 20 | Jeremy Hill | CIN | CLE |
| 21 | Isaiah Crowell | CLE | at CIN |
| 22 | Christine Michael | SEA | at ARI |
| 23 | Rashad Jennings | NYG | at LA |
| 24 | Jamaal Charles | KC | NO |
| 25 | Frank Gore | IND | at TEN |
| 26 | T.J. Yeldon | JAX | OAK |
| 27 | Jay Ajayi | MIA | BUF |
| 28 | Mike Davis | SF | TB |
| 29 | Duke Johnson Jr. | CLE | at CIN |
| 30 | Matt Forte | NYJ | BAL |
| 31 | LeGarrette Blount | NE | at PIT |
| 32 | Chris Ivory | JAX | OAK |
| 33 | Ryan Mathews | PHI | MIN |
| 34 | Bilal Powell | NYJ | BAL |
| 35 | Shaun Draughn | SF | TB |
| 36 | Bobby Rainey | NYG | at LA |
| 37 | Latavius Murray | OAK | at JAX |
| 38 | Arian Foster | MIA | BUF |
| 39 | Jerrick McKinnon | MIN | at PHI |
| 40 | Mike Gillislee | BUF | at MIA |
| 41 | Chris Thompson | WSH | at DET |
| 42 | Darren Sproles | PHI | MIN |
| 43 | Don Xzaviar Jackson | GB | CHI |
| 44 | Devontae Booker | DEN | HOU |
| 45 | Knile Davis | GB | CHI |
| 46 | C.J. Spiller | SEA | at ARI |
| 47 | Derrick Henry | TEN | IND |
| 48 | Travaris Cadet | NO | at KC |
| 49 | Ka’Deem Carey | CHI | at GB |
| 50 | Kenneth Dixon | BAL | at NYJ |
** Bye Weeks: Cowboys & Panthers **