By The Hudsonian, Joshua Hudson
| Click Here for: | QB | WR | TE | FLEX | D/ST |
| Player | Team | Opponent | |
| 1 | Todd Gurley II | LAR | ARI |
| 2 | Alvin Kamara | NO | CLE |
| 3 | Melvin Gordon | LAC | @ BUF |
| 4 | James Conner | PIT | KC |
| 5 | Ezekiel Elliott | DAL | NYG |
| 6 | David Johnson | ARI | @ LAR |
| 7 | Saquon Barkley | NYG | @ DAL |
| 8 | Jordan Howard | CHI | SEA |
| 9 | Jay Ajayi | PHI | @ TB |
| 10 | Adrian Peterson | WAS | IND |
| 11 | Dion Lewis | TEN | HOU |
| 12 | Chris Thompson | WAS | IND |
| 13 | Christian McCaffrey | CAR | @ ATL |
| 14 | Dalvin Cook | MIN | @ GB |
| 15 | Isaiah Crowell | NYJ | MIA |
| 16 | Leonard Fournette | JAX | NE |
| 17 | Kareem Hunt | KC | @ PIT |
| 18 | Lamar Miller | HOU | @ TEN |
| 19 | James White | NE | @ JAX |
| 20 | Tevin Coleman | ATL | CAR |
| 21 | Kenyan Drake | MIA | @ NYJ |
| 22 | Matt Breida | SF | DET |
| 23 | Rex Burkhead | NE | @ JAX |
| 24 | Carlos Hyde | CLE | @ NO |
| 25 | Joe Mixon | CIN | BAL |
| 26 | Devonta Freeman | ATL | CAR |
| 27 | Duke Johnson Jr. | CLE | @ NO |
| 28 | Alex Collins | BAL | @ CIN |
| 29 | Royce Freeman | DEN | SEA |
| 30 | Austin Ekeler | LAC | @ BUF |
| 31 | LeSean McCoy | BUF | LAC |
| 32 | Jamaal Williams | GB | MIN |
| 33 | Alfred Morris | SF | DET |
| 34 | Philip Lindsay | DEN | SEA |
| 35 | Bilal Powell | NYJ | MIA |
| 36 | Derrick Henry | TEN | HOU |
| 37 | Chris Carson | SEA | @ DEN |
| 38 | Javorious “Buck” Allen | BAL | @ CIN |
| 39 | Marshawn Lynch | OAK | @ DEN |
| 40 | Rashaad Penny | SEA | @ DEN |
| 41 | Peyton Barber | TB | PHI |
| 42 | Tarik Cohen | CHI | SEA |
| 43 | Kerryon Johnson | DET | @ SF |
| 44 | Ty Montgomery | GB | MIN |
| 45 | Marlon Mack | IND | @ WAS |
| 46 | Theo Riddick | DET | @ SF |
| 47 | Nyheim Hines | IND | @ WAS |
| 48 | T.J. Yeldon | JAX | NE |
| 49 | Darren Sproles | PHI | @ TB |
| 50 | Jordan Wilkins | IND | @ WAS |
| 51 | Jalen Richard | OAK | @ DEN |
| 52 | Corey Clement | PHI | @ TB |
| 53 | Frank Gore | MIA | @ NYJ |
| 54 | C.J. Anderson | CAR | @ ATL |
| 55 | Devontae Booker | DEN | SEA |
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