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Fantasy Football Week 17 Start/Sit: Matchups to Target and Avoid

Fantasy Football 2025

Welcome to Club Fantasy’s Weekly Start/Sit Matchup Report, a data-driven guide to setting winning lineups. Each week, we highlight the defenses allowing the most and fewest fantasy points to quarterbacks, running backs, wide receivers, and tight ends over the last four weeks.

This article doesn’t just provide season-long data you’ll find on most sites; it’s recent, actionable info to help you spot hot and cold matchups before your competition does. Use it to guide your start/sit decisions or build a DFS lineup that can win the slate.

Here are the fantasy matchups to target and avoid for NFL Week 17.

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Fantasy Football Week 17 Start Sit Advice

Scoring Note: These rankings use the full PPR scoring format. However, there is not a big difference between the rankings in .5 or non-PPR scoring.

Quarterback Matchups

Most Points Allowed Last 4 Weeks (Matchups to Target)

  1. DAL: plays @ WAS, consider Marcus Mariota, if he plays
  2. TEN: plays NO, consider Tyler Shough
  3. DEN: plays @ KC, consider Chris Oladokun
  4. TB: plays @ MIA, consider Quinn Ewers
  5. GB: plays BAL, consider Lamar Jackson
  6. NYJ: plays NE, consider Drake Maye
  7. LAR: plays @ ATL, consider Kirk Cousins
  8. PIT: plays @ CLE, consider Shedeur Sanders
  9. ARI: plays @ CIN, consider Joe Burrow
  10. DET: plays @ MIN, consider Max Brosmer

Fewest Points Allowed Last 4 Weeks (Matchups to Fade)

  1. MIN: plays DET, fade Jared Goff
  2. PHI: plays @ BUF, fade Josh Allen
  3. NO: plays @ TEN, fade Cam Ward
  4. SEA: plays @ CAR, fade Bryce Young
  5. JAX: plays @ IND, fade Philip Rivers

Running Back Matchups

Most Points Allowed Last 4 Weeks (Matchups to Target)

  1. ARI: plays @ CIN, consider Chase Brown
  2. NYJ: plays NE, consider Rhamondre Stevenson and TreVeyon Henderson, if he plays
  3. CLE: plays PIT, consider Jaylen Warren and Kenneth Gainwell
  4. NE: plays @ NYJ, consider Breece Hall
  5. DET: plays @ MIN, consider Aaron Jones and Jordan Mason, if he plays
  6. WAS: plays DAL, consider Javonte Williams
  7. CIN: plays ARI, consider Michael Carter
  8. BUF: plays PHI, consider Saquon Barkley
  9. LV: plays NYG, consider Tyrone Tracy Jr. and Devin Singletary
  10. DAL: plays @ WAS, consider Chris Rodriguez and Jacory Croskey-Merritt

Fewest Points Allowed Last 4 Weeks (Matchups to Fade)

  1. LAC: plays HOU, fade Woody Marks and Jawhar Jordan
  2. CHI: plays @ SF, fade Christian McCaffrey
  3. ATL: plays LAR, fade Kyren Williams and Blake Corum
  4. DEN: plays @ KC, fade Isiah Pacheco and Kareem Hunt
  5. TEN: plays NO, fade Audric Estime and Alvin Kamara, if he plays

Wide Receiver Matchups

Most Points Allowed Last 4 Weeks (Matchups to Target)

  1. DET: plays @ MIN, consider Justin Jefferson and Jordan Addison
  2. GB: plays BAL, consider Zay Flowers
  3. DAL: plays @ WAS, consider Terry McLaurin and Deebo Samuel
  4. LAR: plays @ ATL, consider Drake London and Darnell Mooney
  5. IND: plays JAX, consider Jakobi Meyers, Brian Thomas, and Parker Washington
  6. CAR: plays SEA, consider Jaxson Smith-Njigba
  7. ATL: plays LAR, consider Puka Nacua
  8. CHI: plays @ SF, consider Jauan Jennings
  9. DEN: plays @ KC, consider Rashee Rice, if he plays
  10. BAL: plays @ GB, consider Jayden Reed, Romeo Doubs, and Christian Watson, if he plays

Fewest Points Allowed Last 4 Weeks (Matchups to Fade)

  1. PHI: plays @ BUF, fade Khalil Shakir
  2. CIN: plays ARI, fade Michael Wilson and Marvin Harrison Jr.
  3. NO: plays @ TEN, fade Chimere Dike
  4. MIN: plays DET, fade Amon-Ra St. Brown and Jameson Williams
  5. BUF: plays PHI, fade A.J. Brown and DeVonta Smith

Tight End Matchups

Most Points Allowed Last 4 Weeks (Matchups to Target)

  1. TB: plays @ MIA, consider Darren Waller
  2. CIN: plays ARI, consider Trey McBride
  3. MIA: plays TB, consider Cade Otton
  4. WAS: plays DAL, consider Jake Ferguson
  5. PIT: plays @ CLE, consider Harold Fannin
  6. HOU: plays @ LAC, consider Oronde Gadsden
  7. TEN: plays NO, consider Juwan Johnson, and maybe Taysom Hill
  8. DEN: plays @ KC, consider Travis Kelce
  9. NYJ: plays NE, consider Hunter Henry
  10. ARI: plays @ CIN, consider Mike Gesicki

Fewest Points Allowed Last 4 Weeks (Matchups to Fade)

  1. MIN: plays DET, fade Anthony Firkser and Shane Zylstra
  2. CAR: plays SEA, fade AJ Barner
  3. JAX: plays @ IND, fade Tyler Warren
  4. PHI: plays @ BUF, fade Dalton Kincaid
  5. NYG: plays @ LV, fade Brock Bowers

Are you looking for more help with NFL Week 17?

Here are Club Fantasy’s Week 17 rankings! Also, you’ll find the rest of our fantasy football articles here!

Finally, don’t forget to tune into our YouTube channel every Wednesday at 8 pm EST for No Punt Intended. Josh, Joe, and Ryan will help get you ready for your Week 17 fantasy matchups!


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