Fantasy Football Week 6 Start/Sit: Matchups to Target and Avoid

Club Fantasy’s Weekly Fantasy Football Matchup Report is here to help you set winning lineups. Unlike season-long fantasy points allowed rankings, our report focuses on the last four weeks, giving you a better look at how defenses are performing right now. Each week, we highlight the ten defenses allowing the most points to QBs, RBs, WRs, and TEs, along with the five toughest matchups. Use this recent data to guide your start/sit decisions or build a DFS lineup that can win the slate. Here are the matchups to target and avoid for NFL Week 6.

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Fantasy Football Week 6 Start/Sit Advice

Scoring Note: These rankings use the full PPR scoring format. However, there is not a big difference between the rankings in .5 or non-PPR scoring.

Quarterback Matchups

Most Points Allowed Last 4 Weeks (Matchups to Target):

1. DET: BYE.
2. ARI: plays @ LAR, consider Matthew Stafford.
3. BUF: plays @ LV, consider Kirk Cousins.
4. WAS: plays @ SF, consider Brock Purdy.
5. LV: plays vs BUF, consider Josh Allen.
6. ATL: plays vs CHI, consider Caleb Williams.
7. DAL: plays @ GB, consider Jordan Love.
8. MIA: BYE.
9. IND: plays vs TEN, consider Cam Ward.
10. NYG: plays vs NO, consider Tyler Shough.

Fewest Points Allowed Last 4 Weeks (Matchups to Fade):

1. MIN: BYE.
2. GB: plays vs DAL, fade Dak Prescott.
3. CHI: plays @ ATL, fade Michael Penix Jr.
4. HOU: plays @ JAX, fade Trevor Lawrence.
5. SEA: plays @ DEN, fade Bo Nix.

Running Back Matchups

Most Points Allowed Last 4 Weeks (Matchups to Target):

1. NO: plays @ NYG, consider Cam Skattebo and Najee Harris.
2. GB: plays vs DAL, consider Javonte Williams.
3. NYJ: plays @ NE, consider Rhamondre Stevenson.
4. BUF: plays @ LV, consider Breece Hall and Braelon Allen.
5. MIA: BYE.
6. LV: plays vs BUF, consider James Cook.
7. DAL: plays @ GB, consider MarShawn Lloyd.
8. SF: plays vs WAS, consider Jacory Croskey-Merritt and Rachaad White.
9. IND: plays vs TEN, consider Tony Pollard and Tyjae Spears.
10. ARI: plays @ LAR, consider Kyren Williams and Blake Corum.

Fewest Points Allowed Last 4 Weeks (Matchups to Fade):

1. TB: plays vs PIT, fade Jaylen Warren and Rico Dowdle.
2. CHI: plays @ ATL, fade Bijan Robinson and Brian Robinson.
3. BAL: plays @ CLE, fade Quinshon Judkins and Jaleel McLaughlin.
4. MIN: BYE.
5. DET: BYE.

Wide Receiver Matchups

Most Points Allowed Last 4 Weeks (Matchups to Target):

1. BUF: plays @ LV, consider Tre Tucker and Cody White.
2. WAS: plays @ SF, consider Mike Evans and Brandin Cooks.
3. ATL: plays vs CHI, consider Rome Odunze, Luther Burden III, and Kalif Raymond.
4. HOU: plays @ JAX, consider Parker Washington, Jakobi Meyers, and Brian Thomas Jr..
5. JAX: plays vs HOU, consider Nico Collins and Marvin Harrison Jr.
6. ARI: plays @ LAR, consider Puka Nacua and Davante Adams.
7. DAL: plays @ GB, consider Christian Watson and Matthew Golden.
8. PHI: plays vs CAR, consider Tetairoa McMillan and Jalen Coker.
9. BAL: plays @ CLE, consider KC Concepcion and Denzel Boston.
10. TEN: plays @ IND, consider Josh Downs and Keenan Allen.

Fewest Points Allowed Last 4 Weeks (Matchups to Fade):

1. MIN: BYE.
2. LAR: plays vs ARZ, fade Michael Wilson and Kendrick Bourne.
3. MIA: BYE.
4. KC: plays vs LAC, fade Ladd McConkey, Quentin Johnston, and Tre’ Harris.
5. CAR: plays @ PHI, fade DeVonta Smith, Dontayvion Wicks, and Makai Lemon.

Tight End Matchups

Most Points Allowed Last 4 Weeks (Matchups to Target):

1. DET: BYE.
2. KC: plays vs LAC, consider Oronde Gadsden II.
3. LV: plays vs BUF, consider Dalton Kincaid.
4. MIA: BYE.
5. WAS: plays @ SF, consider George Kittle.
6. ARI: plays @ LAR, consider Tyler Higbee.
7. CIN: BYE.
8. CAR: plays @ PHI, consider Dallas Goedert.
9. NO: plays @ NYG, consider Isaiah Likely.
10. IND: plays vs TEN, consider Gunnar Helm.

Fewest Points Allowed Last 4 Weeks (Matchups to Fade):

1. MIN: BYE.
2. LAR: plays vs ARZ, fade Trey McBride.
3. HOU: plays @ JAX, fade Brenton Strange.
4. LAC: plays @ KC, fade Travis Kelce.
5. CHI: plays @ ATL, fade Kyle Pitts.

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Looking for more help with NFL Week 6?

Here are Club Fantasy’s Week 6 rankings! Also, you’ll find the rest of our fantasy football articles here!

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