Fantasy Football Matchup Report: Starts and Sits for Week 6

Club Fantasy’s Weekly Fantasy Football Matchup Report is here to help you set winning lineups. Each week, we spotlight the ten defenses allowing the most points to QBs, RBs, WRs, and TEs, along with the five toughest matchups. Starting this week, our data will reflect each team’s performance over the last four weeks, rather than season-long statistics. With bye weeks starting, this analysis will focus on a team’s last three or four games, providing a more precise and actionable picture of which matchups to target or avoid based on recent performance. Use this info to guide your start/sit decisions or build a DFS lineup that can win the slate.

Here are the matchups to target and fade for NFL Week 6.

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Week 6 Fantasy Football Matchups

Scoring Note: These rankings use the full PPR scoring format. However, there is not a big difference between the rankings in .5 or non-PPR scoring.

Quarterback Matchups

Most Points Allowed (Last 4 Weeks): Matchups to Target

1. DAL: plays @ CAR, start Bryce Young
2. MIA: plays LAC, start Justin Herbert
3. BAL: plays LAR, start Matthew Stafford
4. NO: plays NE, start Drake Maye
5. CIN: plays @ GB, start Jordan Love
6. WAS: plays CHI, start Caleb Williams
7. TB: plays SF, start Brock Purdy or Mac Jones
8. JAX: plays SEA, start Sam Darnold
9. LAR: plays @ BAL, start Lamar Jackson or Cooper Rush
10. PIT: plays CLE, start Dillon Gabriel

Fewest Points Allowed (Last 4 Weeks): Matchups to Fade

1. HOU: BYE
2. MIN: BYE
3. ATL: plays BUF, fade Josh Allen
4. BUF: plays @ ATL, fade Michael Penix
5. LAC: plays @ MIA, fade Tua Tagovailoa

Running Back Matchups

Most Points Allowed (Last 4 Weeks): Matchups to Target

1. CIN: plays @ GB, start Josh Jacobs
2. CHI: plays @ WAS, start Bill Croskey-Merritt
3. BAL: plays LAR, start Kyren Williams
4. TEN: plays @ LV, start Ashton Jeanty
5. MIA: plays LAC, start Kimani Vidal and Hassan Haskins
6. DAL: plays @ CAR, start Chuba Hubbard and Rico Dowdle
7. ARI: plays @ IND, start Jonathan Taylor
8. MIN: BYE
9. KC: plays DET, start Jahmyr Gibbs and David Montgomery
10. NYG: plays PHI, start Saquon Barkley or Tank Bigsby/Will Shipley

Fewest Points Allowed (Last 4 Weeks): Matchups to Fade

1. ATL: plays BUF, fade James Cook
2. CLE: plays @ PIT, fade Jaylen Warren and Kenneth Gainwell
3. LAR: plays @ BAL, fade Derrick Henry
4. GB: plays CIN, fade Chase Brown
5. IND: plays ARI, fade Michael Carter and Emari Demercado

Wide Receiver Matchups

Most Points Allowed (Last 4 Weeks): Matchups to Target

1. DAL: plays @ CAR, start Tetairoa McMillan and Xavier Legette
2. NYG: plays PHI, start A.J. Brown and DeVonta Smith
3. IND: plays ARI, start Marvin Harrison Jr.
4. BAL: plays LAR, start Puka Nacua and Davante Adams
5. CLE: plays @ PIT, start DK Metcalf
6. PIT: plays CLE, start Jerry Jeudy
7. JAX: plays SEA, start Jaxson Smith-Njigba
8. LV: plays TEN, start Calvin Ridley and Elic Ayomanor
9. WAS: plays CHI, start Rome Odunze and DJ Moore
10. CHI: plays @ WAS, start Deebo Samuel and (maybe) Terry McLaurin

Fewest Points Allowed (Last 4 Weeks): Matchups to Fade

1. MIN: BYE
2. KC: plays DET, fade Amon-Ra St. Brown and Jameson Williams
3. CAR: plays DAL, fade CeeDee Lamb and George Pickens
4. HOU: BYE
5. LAC: plays @ MIA, fade Jaylen Waddle

Tight End Matchups

Most Points Allowed (Last 4 Weeks): Matchups to Target

1. PIT: plays CLE, start David Njoku and Harold Fannin
2. CAR: plays DAL, start Jake Ferguson
3. CIN: plays @ GB, start Tucker Kraft
4. GB: plays CIN, start Mike Gesicki or Noah Fant
5. MIN: BYE
6. CHI: plays @ WAS, start Zach Ertz
7. SF: plays @ TB, start Cade Otton
8. NO: plays NE, start Hunter Henry
9. WAS: plays CHI, start Cole Kmet or Colston Loveland
10. DAL: plays @ CAR, start Ja’Tavian Sanders or Tommy Tremble

Fewest Points Allowed (Last 4 Weeks): Matchups to Fade

1. ATL: plays BUF, fade Dalton Kincaid
2. KC: plays DET, fade Sam LaPorta
3. BUF: plays @ ATL, fade Kyle Pitts
4. LAC: plays @ MIA, fade Darren Waller
5. LV: plays TEN, fade Chigoziem Okonkwo

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Are you looking for more help with NFL Week 6?

Here are Club Fantasy’s Week 6 rankings! Also, you’ll find the rest of our fantasy football articles here!

Finally, don’t forget to tune into our YouTube channel every Wednesday at 8 pm EST for No Punt Intended. Josh, Joe, and Ryan will help get you ready for your Week 5 fantasy matchups!