By The Hudsonian, Joshua Hudson
| Click Here for: | QB | WR | FLEX | TE | D/ST |
| Player | Team | Opponent | |
| 1 | Le’Veon Bell | PIT | @HOU |
| 2 | Todd Gurley | LAR | @TEN |
| 3 | Leonard Fournette | JAX | @SF |
| 4 | Alvin Kamara | NO | ATL |
| 5 | Ezekiel Elliott | DAL | SEA |
| 6 | Kareem Hunt | KC | MIA |
| 7 | Mark Ingram | NO | ATL |
| 8 | Melvin Gordon | LAC | @NYJ |
| 9 | Christian McCaffrey | CAR | TB |
| 10 | Dion Lewis | NE | BUF |
| 11 | LeSean McCoy | BUF | @NE |
| 12 | Devonta Freeman | ATL | @NO |
| 13 | Jerick McKinnon | MIN | @GB |
| 14 | DeMarco Murray | TEN | LAR |
| 15 | Lamar Miller | HOU | PIT |
| 16 | Jordan Howard | CHI | CLE |
| 17 | Duke Johnson Jr. | CLE | @CHI |
| 18 | Joe Mixon | CIN | DET |
| 19 | Latavius Murray | MIN | @GB |
| 20 | Alex Collins | BAL | IND |
| 21 | Kerwynn Williams | ARI | NYG |
| 22 | Jamaal Williams | GB | MIN |
| 23 | Carlos Hyde | SF | JAX |
| 24 | Samaje Perine | WSH | DEN |
| 25 | Kenyan Drake | MIA | @KC |
| 26 | Theo Riddick | DET | @CIN |
| 27 | Isaiah Crowell | CLE | @CHI |
| 28 | C.J. Anderson | DEN | @WSH |
| 29 | Jay Ajayi | PHI | OAK |
| 30 | Bilal Powell | NYJ | LAC |
| 31 | Frank Gore | IND | @BAL |
| 32 | Marshawn Lynch | OAK | @PHI |
| 33 | Jonathan Stewart | CAR | TB |
| 34 | Mike Davis | SEA | @DAL |
| 35 | Danny Woodhead | BAL | IND |
| 36 | Derrick Henry | TEN | LAR |
| 37 | Javorius Allen | BAL | IND |
| 38 | Elijah McGuire | NYJ | LAC |
| 39 | James White | NE | BUF |
| 40 | J.D. McKissic | SEA | @DAL |
| 41 | Tarik Cohen | CHI | CLE |
| 42 | Rod Smith | DAL | SEA |
| 43 | Marlon Mack | IND | @BAL |
| 44 | Wayne Gallman | NYG | @ARI |
| 45 | Giovani Bernard | CIN | DET |
| 46 | Orleans Darkwa | NYG | @ARI |
| 47 | D.J. Foster | ARI | NYG |
| 48 | LeGarrette Blount | PHI | OAK |
| 49 | Ameer Abdullah | DET | @CIN |
| 50 | DeAndre Washington | OAK | @PHI |